1. Turmeric has anti-epileptogenic effect
The brain is divided into four lobes of which one is temporal lobe. Temporal lobe epilepsy is a very common form of partial epilepsy. During such a seizure there can be memory loss or change in sensory functions.
Kiasalari et al conducted an animal study to examine the effect of curcumin on temporal lobe epilepsy seizures.
It was observed that curcumin pretreatment reduced susceptibility to seizures, reduced oxidative stress( an imbalance between prooxidant and antioxidant agents in the body) and reduced loss and damage of brain cells.
Epileptogenesis is the sequence of events that occur prior to a seizure and lead to onset of seizures.
Curcumin administration attenuates severity of recurrent seizures and protects other brain function like cognition and is useful in modifying epileptogenesis.
Status epilepticus is defined as a seizure spanning over a time period of 30 minutes or two seizures within this time period without recovery. It is a severe form of epilepsy that requires immediate medical attention.
Curcumin as an anticonvulsant and antioxidant can serve to be therapeutic in status epilepticus. It is proven to ameliorate cognitive dysfunction and oxidative stress occurring in status epilepticus.
Liposomal curcumin, a novel formulation of curcumin, is found to effective in treating status epilepticus.
However there is one study in which researchers comment that oral curcumin does not affect chronic seizure and this could be due to its low bioavailability.